Why is having basic understanding of bone ossification important for Anatomy and Physiology students?
Having basic knowledge of bone ossification and how it forms the foundation of bone development and growth is crucial for those going into the medical field. Ossification impacts the structure, function, and repair of the skeletal system, and is essential for understanding various clinical conditions affecting bones.
Levels of Ossification
Resting/Quiescent: Contains small, inactive chondrocytes.
Proliferation/Growth: Chondrocytes undergo rapid mitosis.
Hypertrophic: Chondrocytes enlarge and become hypertrophic
Calcification: The cartilage matrix calcifies, cutting off nutrients to hypertrophic chondrocytes.
Ossification: Osteoblasts invade and deposit new bone matrix.
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